Study Shows Poor Sleep Linked to Alzheimer’s Disease



 The toxic protein beta-amyloid, depicted in red on the right side of the brain, is linked to insufficient sleep and may be paving the way for Alzheimer's disease. On the left, you can see a brain free of beta-amyloid and benefiting from brain waves produced during deep sleep. 


A new pathway by which Alzheimer's disease may lead to memory loss in later life has been identified in a study from UC B E R K E L E Y that was recently published. 


Researchers at UC Berkeley have discovered compelling evidence that the beta-amyloid protein that is thought to be the cause of Alzheimer's disease attacks the brain's long-term memory through poor sleep, particularly a lack of the deep, restorative slumber required to hit the save button on memories


The senior author of the study that was published in the journal Nature Neuroscience, UC Berkeley neuroscience professor Matthew Walker, stated, "Our findings reveal a new pathway through which Alzheimer's disease may cause memory decline later in life ". 


Extreme stores of beta-amyloid are key suspects in the pathology of Alzheimer's disease, a harmful type of dementia brought about by the slow passing of synapses. One of the world's fastest-growing and most debilitating public health issues is expected to be Alzheimer's disease, which has been diagnosed in more than 40 million people. This is due to the unprecedented aging wave of baby boomers. 


According to Walker, the good news about the findings is that poor sleep may be treatable and can be improved through exercise, behavioral therapy, and even electrical stimulation that amplifies brain waves while a person is sleeping. This technology has been used successfully to improve overnight memory in young adults


Walker stated, "This discovery offers hope". Sleep may be a novel therapeutic target for combating memory loss in older adults and even dementia patients.


A Power Cleanse For The Brain

A significant grant from the National Institutes of Health has been awarded to UC Berkeley researchers to investigate sleep as a biomarker for Alzheimer's disease. In the brains of 26 elderly people, researchers looked for a connection between poor sleep, poor memory, and the toxic accumulation of beta-amyloid proteins.


Patients with Alzheimer's disease and individuals with sleep disorders have both shown signs of beta-amyloid accumulation. Poor-quality sleep has been linked to the deterioration of this frontal brain region in the elderly. Toxic proteins are being flushed out of the body during the night by sleep, preventing their accumulation


A vicious cycle

Participants were asked to memorize 120 word pairs and then tested on how well they remembered some of them following PET scans for biomarkers of Alzheimer's disease


According to Walker, having more beta-amyloid in particular regions of the brain results in less deep sleep and, as a result, worse memory. Also, the less profound rest you have, the less viable you are at getting out this terrible protein. It's a never-ending cycle. 


However, we do not yet know which of these two factors, poor sleep or poor protein, initiates this cycle first. Which finger flicks the first domino, thereby initiating the cascade? Walker expanded. 


As they follow a brand-new group of elderly people over the course of the next five years, the researchers will come to this conclusion. 


Man D E R stated, "This is a new pathway linking Alzheimer's disease to memory loss, and it's important because we can do something about it"

Comments

Post a Comment

Popular posts from this blog

What Is Difference Between Chia Seeds And Flaxseed

Image
  Certain seeds have gained a reputation as superfoods in recent years. Examples include the well-known chia and flax seeds. Both have been linked to health benefits such as a healthier heart, lower blood sugar levels, and protection against certain types of cancer. However, many people wonder which of the two seeds is actually the healthiest. Both are extremely rich in nutrients. To answer this question, this article looks at the scientific evidence that supports each The Saliva Hispanic plant, more commonly referred to as the chia plant, is the source of the tiny oval-shaped chia seeds. Chia seeds are slightly larger and flatter than flax seeds. Flax seeds, on the other hand, have a slightly nuttier flavor than chia seeds. However, incorporating both kinds of seeds into a variety of dishes is simple Nutrition comparison Comparative analysis of the nutrients present in chia and flax seeds The major nutrients contained in a 1-ounce (28-gram) serving, or approximately 4 tablespoons,...
Read more

Overconsumption of Common Red Food Dye May Lead to Inflammatory Bowel Disease

Image
  Allure Red AC, a synthetic dye found in popular foods like Skittles, Doritos, Gatorade, Jell-O, and Fruit Loops, has been linked to an increased risk of developing inflammatory bowel diseases (I-B D S) such as Crohn's disease and ulcerative colitis if consumed frequently. The dye, also known as FD & C Red 40 and Food Red 17, is thought to have negative effects on gut health and increase inflammation, according to a small study done on laboratory mice. The study, which was recently published in Nature Communications, found that the additive directly breaks the gut barrier, which helps keep bacteria from getting in, and that it also makes more serotonin, a hormone and neurotransmitter in the gut. According to the report, this reaction alters the microbiome of the gut, making people more likely to develop inflammatory bowel conditions. What we have found is striking and alarming, as this common synthetic food dye may be a dietary trigger for I-B D S, said senior author W-A L-I U...
Read more

Border violence displaces 76,000 in Lebanon: Hezbollah

 The International Organization for Migration (IOM) of the United Nations reported on Friday that nearly three months of nearly daily fighting along the border with Israel had resulted in the displacement of more than 76,000 people in Lebanon. The boundary region has seen a flood of viciousness since early October, with blow for blow trades of fire forging ahead with Friday between Israeli powers and Hezbollah. In a report distributed on Thursday, the IOM said that the heightening had uprooted 76,018 individuals, predominantly in areas of southern Lebanon lining Israel. More than 80% of the dislodged Lebanese are remaining with family members, as per the report, and just two percent housed in 14 aggregate sanctuaries spread across the south of the country, predominantly in the seaside city of Tire and in the Hasbaya locale. The remainder, according to the UN agency, have relocated to homes or apartments further from the border. Cross-line brutality has left 175 individuals dead in ...
Read more